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ZENODO
Published
2026-02-27
Section
Articles
How to Cite
How to Cite
CLINICAL-ANAMNESTIC AND PATHOMORPHOLOGICAL CHARACTERISTICS OF ESOPHAGEAL MALIGNANT NEOPLASMS AMONG THE POPULATION OF THE FERGANA VALLEY
Sadikova Umida
Senior Lecturer, Department of Social Hygiene and Healthcare Management
Keywords: Esophageal cancer, Fergana Valley, Squamous cell carcinoma, Pathomorphology, Clinical anamnesis, Biostatistics, Risk factors, Oncology.
Abstract
This study examines the clinical-anamnestic and pathomorphological features of esophageal cancer (EC) within the Fergana Valley population. A comprehensive analysis of 142 patients (2019–2024) was conducted to identify regional risk factors and histological patterns. Results indicate a high prevalence of Squamous Cell Carcinoma (82.4%), with a significant correlation between chronic thermal mucosal injury (hot tea consumption >65°C) and advanced tumor stages. Statistical analysis revealed that 64.8% of patients were diagnosed at Stage III-IV, emphasizing a critical delay in medical consultation. Histopathologically, moderately (G2) and poorly differentiated (G3) tumors predominated. The study concludes that regional dietary habits and late-stage detection are the primary drivers of high mortality, necessitating targeted endoscopic screening protocols for the Fergana Valley.
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