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2025-08-16
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Articles
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MIYA ENERGIYA METABOLIZMI – ASOSIY YO‘LLAR VA MUHIM MODDALAR
Rayimqulov Firdavs Azimjon o‘g‘li
Alfraganus Universiteti Tibbiyot fakulteti 2-kurs talabasi ORCID ID: 0009-0004-0348-2962
To‘lqinov Hamidulla Xamdam o‘g‘li
Alfraganus Universiteti Tibbiyot fakulteti 2-kurs talabasi Ilmiy rahbar: kimyo fanlari falsafa doktori (PhD)
Xaydarov Islom Norboy o‘g‘li
Alfraganus Universiteti Farmasevtika va kimyo kafedrasi katta o‘qituvchisi ORCID ID: 0009-0000-2490-4301
##semicolon## Miya metabolizmi, glyukoza, glyukoliz, oksidlovchi fosforlanish, astrosit-neyron aloqasi, energiya substratlari, ishemiya, neyrofiziologiya
सार
Miya organizmdagi eng metabolik faol a’zo bo‘lib, tana og‘irligining atigi 2% ini tashkil etganiga qaramay, umumiy kislorod iste’molining 20% dan ortig‘ini, glyukozaning esa taxminan 25% ini sarflaydi. Bu energiya talabi asosan neyronlarning bioelektrik faolligi, ion gradientlarini saqlash, sinaptik uzatish va plastiklik jarayonlarini qo‘llab-quvvatlashga yo‘naltirilgan. Ushbu maqolada miya energiya metabolizmining asosiy yo‘llari — glyukoliz, sitrat sikli va oksidlovchi fosforlanish, shuningdek, asosiy substratlar — glyukoza, laktat va keton jismlarining roli tahlil qilinadi. Shuningdek, astrositlar va neyronlar o‘rtasidagi metabolik aloqalar, ishemik holatlarda metabolik muvozanatning buzilishi va zamonaviy tadqiqotlarning klinik ahamiyati yoritiladi.
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